The recycle bin awaits...
Ref. Dawes, D., Ho, J., Cole, J., Reardon, R., Lundin, E., Terwey, K., Falvey, D., & Miner, J. (2010). Effect of an Electronic Control Device Exposure on a Methamphetamine-intoxicated Animal Model, Academic Emergency Medicine, 17 (4), 436-443 DOI: 10.1111/j.1553-2712.2010.00708.x
If You're Going to Taser a Sheep, at Least Do It Right!
...in this experiment the authors have failed profoundly in their anesthesia choice. ...in a study designed to look at the incidence of cardiac arrythmia, these folks used an anesthesia well-documented to have effects on the L-type calcium channel and calcium in the heart... You can't study cardiac and vascular regulation when you use an agent that directly affects them. So, we don't use it. ...So, it's unclear how the effects of methamphetamine and exposure of the TASER are supposed to be teased apart from the influence of isoflurane on cardiac contractile function. It's also unclear how to interpret the dosages of methamphetamine and electrical current from a risk management standpoint. If you're going to do a study, it's great to use anesthesia, but you have to be very certain that you know how that anesthesia works and its potential to confound your work. Otherwise, your data are really not useful. [LINK]
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